Polyvinyl alcohol hydrogels for capsules formulation

N. Soussi, S. Moulay, N. Chafi

Abstract


Abstract : Poly(vinyl alcohol)-based hydrogels were prepared by freeze-thaw cycles (FT) and room temperature (RT) methods, in the presence of increasing proportions of sodium carbonate. Films from these hydrogels were characterized by ATR-FTIR, SEM, TGA/DSC, optical microscopy, and by their mechanical properties. The results of thermal analyses revealed that Tgs of the films from hydrogels made from RT were higher than those from FT method. Mechanical tests indicated the creation of significant free volumes between the PVA chains in the hydrogels of FT method. And, their mechanical stretching caused their chains to slip. However, the PVA chains from RT method were arranged in a star-like morphology, leading to their disassembling upon stretching. Overall, the global results of this study are promising for future applications in biomedicals, particularly in capsules making.


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References


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